Submit Manuscript  

Article Details


Invertebrate FMRFamide Related Peptides

[ Vol. 20 , Issue. 6 ]

Author(s):

Kevin G. Krajniak   Pages 647 - 670 ( 24 )

Abstract:


In 1977 the neuropeptide FMRFamide was isolated from the clam, Macrocallista nimbosa. Since then several hundred FMRFamide-related peptides (FaRPs) have been isolated from invertebrate animals. Precursors to the FaRPs likely arose in the cnidarians. With the transition to a bilateral body plan FaRPs became a fixture in the invertebrate phyla. They have come to play a critical role as neurotransmitters, neuromodulators, and neurohormones. FaRPs regulate a variety of body functions including, feeding, digestion, circulation, reproduction, movement. The evolution of the molecular form and function of these omnipresent peptides will be considered.

Keywords:

FMRFamide, FaRPs, cnidaria, platyhelminthes, nematoda, annelida, mollusca, arthropoda.

Affiliation:

Department of Biological Sciences, Southern Illinois University Edwardsville, Illinois Box 1651, Edwardsville, IL 62026-1651, USA.



Read Full-Text article