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Recent Advances in X-Ray Hydroxyl Radical Footprinting at the Advanced Light Source Synchrotron

Author(s):

Simon A. Morton, Sayan Gupta, Christopher J. Petzold and Corie Ralston*   Pages 1 - 6 ( 6 )

Abstract:


Efforts in the field of synchrotron footprinting are progressing rapidly, with two major footprinting centers in the United States, one on the east coast at the National Synchrotron Light Source II, and one on the west coast at the Advanced Light Source (ALS). This article describes recent technical advances in the technique at the Advanced Light Source, and describes the types of biological problems that can be addressed using the new methods and instrumentation.

Keywords:

synchrotron, footprinting, hydroxyl radical footprinting, x-ray, beamline, radiolysis, radiolytic labeling, Advanced Light Source

Affiliation:

Advanced Light Source Division - Lawrence Berkeley National Laboratory Berkeley, CA, Advanced Light Source Division - Lawrence Berkeley National Laboratory Berkeley, CA, Joint BioEnergy Institute - Lawrence Berkeley National Laboratory Berkeley, CA, Molecular Biology and Integrated Bioimaging Division - Lawrence Berkeley National Laboratory Berkeley, CA



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