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Crystal Structure of Non-Fused Glutathione S-Transferase from Schistosoma 709 japonicum in Complex with Glutathione

[ Vol. 12 , Issue. 7 ]

Author(s):

I. Kursula, A. M. Heape and P. Kursula   Pages 709 - 712 ( 4 )

Abstract:


Schistosoma japonicum glutathione S-transferase (SjGST) is a common fusion tag in recombinant protein production, and its 3-dimensional structure has been studied in the context of drug design. We have determined the crystal structure of non-fused SjGST complexed with glutathione, and compare it to complexes between glutathione and SjGST fusion proteins.

Keywords:

glutathione, gst, crystal structure, fusion protein, schistosoma japonicum

Affiliation:

EMBL-Hamburg/DESY,Notkestrasse 85, D-22603 Hamburg, Germany;



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