Fernando Correa and Chuck S. Farah Pages 241 - 244 ( 4 )
5-Hydroxytyptophan is a fluorescent tryptophan analog that can be incorporated into recombinant proteins expressed in E. coli and is particularly useful in studies of biological systems that involve supermolecular aggregates of more than one protein. Here we review the varied applications of 5-hydroxytryptophan to study structure, interactions, conformational change and dynamics in complex protein systems.
5-hydroxytryptophan, tryptophan, fluorescence, protein structure, protein-protein interactions, protein folding
Departamento de Bioquimica, Instituto de Quimica, Universidade de Sao Paulo, Av. Prof. Lineu Prestes748 Sao Paulo, SP, 05508-000, Brazil.