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Conformation of Di-N-Propyl Glycine Residue in a Glycine Rich Peptide Sequence

[ Vol. 8 , Issue. 4 ]

Author(s):

Kalpana Bhargava and R. Balaji Rao   Pages 307 - 315 ( 9 )

Abstract:


The peptide Boc-(Gly-Dpg-Gly)3-OBzl (I) has been synthesized to examine the conformational preferences of Dpg residues in a peptide sequence rich in glycine, which is known to be a poor helix promoter. The detailed NMR studies revealed that peptide (I) adopts a helical conformation in CDCl3.

Keywords:

Propyl Glycine, Glycine Rich Peptide

Affiliation:

Department of Chemistry, Banaras Hindu University, Varanasi-221005, India.



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